After the latest update, warehouse recipes no longer seem to be craft able at all? existing items are still there, and existing machines still have the recipe set, but if I change the recipe, i cannot change it back, and I cannot set new assemblers to create them. Cannot hand craft either, recipe is totally gone.

This screenshots are from the latest version:

Probably u have encountered an incompatibility bug with another mod.

I have noticed the same thing in my saves, I am going to start looking at the logs.
@Sikjoven: what mods are you using? Maybe we have a few that are the same and can look at them further?

I found this in the current log, that the kr-big-container recipe is not unlockable.

10.295 Script @Krastorio2/lib/private/data-stages/utils/log.lua:99: Krastorio 2|LogLevel:WARNING
10.295 Script @Krastorio2/lib/private/data-stages/utils/log.lua:101: From Krastorio 2->file:Krastorio2/lib/private/data-stages/recipes.lua->function:findNotUnlockableRecipes->line:1883
10.295 Script @Krastorio2/lib/private/data-stages/utils/log.lua:108: Called in->file:...anilla-changes/optional/modify-science-packs-recipes.lua->line:17
10.295 Script @Krastorio2/lib/private/data-stages/utils/log.lua:110: Message: 'This recipes are not unlockable, maybe is an error: { "uranium-rounds-magazine", "nuclear-fuel", "kr-big-active-provider-container", "kr-big-buffer-container", "kr-big-container", "kr-big-passive-provider-container", "kr-big-requester-container", "kr-big-storage-container", "imersite-rounds-magazine" } [from findNotUnlockableRecipes()]'

I solved my issue, I installed Memory Storage (https://mods.factorio.com/mod/deep-storage-unit) and it has a mod setting to Remove krastorio warehouses.