Using my process, fission is actually cheaper than fusion.
Using fusion, one tritium costs (using 1.2 productivity module factor):
25 lithium, 0.83 U235, 4.16 rare metals and yields 47.5GJ (5s * 500MW draw) net power.
Using fission, one uranium fuel cell costs (using 1.4 productivity module factor + reprocessing):
1.43 U235, 1.14 U238, 0.71 steel plate, and yields 4 stone, 0.125 tritium, and 87.5GJ (with 1.75 neighbor factor).
On a per U235 basis:
Fusion -> 57.2 GJ per U235
Fission -> 61.2 GJ per U235 or 66.2 GJ if tritium byproduct is burned
U235 isn't too big of a concern after enrichment is researched. The current advantage of fusion is that the capital cost is slightly less when all of the heat exchange hardware is accounted for, but I am on my first playthrough and after crunching the numbers I don't plan to upgrade my reactor until I can't stretch my current setup to meet my power demand. The logistics of moving just uranium ore and steel plates is easier for me at this point in the game.