There really aren't that many low-value items that you're going to need in many places.
I have a bus for iron, copper, steel, and coal.
All other items I need to move in bulk are only needed in bulk in a single place, so I just use a direct belt.
Krastorio factories are a lot more complex but a lot less resource-intensive than vanilla factories. Red/blue circuits are still going to be your biggest resource sink until you wanna built your first space base (assuming you're playing this with Space Exploration), which point low density structure rivals it.
