Imersite tanks rendering performance when stacked on a belt. Just an empty save with one zigzag belt of Imersite stacked on the belt and I have 41fps.
Steps to reproduce:
1. new game
2. pick sandbox
3. enable all technologies and cheats
4. put an infinity chest with imersite and a loader pointing away from it
5. drag a zig zag belt and end it with a loader pointing to a chest.
6. watch how your fps gets low.
I think other imersite things can cause this too.