I am playing with a 100x tech cost multiplier and getting all of the tech cubes for 100x science is incredibly painful since you cant really scale up the cores very well so I am suggesting to add the following to all techs that use fi_ki_science or fu_ki_science
ignore_tech_cost_multiplier = true,
I have done this on my playthrough and it made it tolerable.
As a bug report I will mention missing localizations when using this with k2so
recipe-name.fu_charger_hydrogen_oxygen
recipe-name.fu_boiler_hydrogen_oxygen
I missed those in the whole migration effort.