Yeah, the problem we saw on discord is that Krastorio 2 spaced out makes so many edits to crafting chains, it currently leaves you totally trapped on Rubia. Like, you can't craft pumpjacks, which I can fix, but then you run into issues with chemplants, and ammo, etc... As I told someone on discord, I could do a quick fix to make on recipe work, but then he'd immediately run into ANOTHER brick wall. I believe it can be made compatible in the future, but until I have some time to really dig in and look at everything, it would just not actually work.
For now, it is marked as incompatible, to stop people from getting softlocked/trapped on Rubia with a completely impossible recipe chain. Sorry!