Hey, thanks for the input!
UPS-wise, the stats are the same of vanilla of course, fluids handling is still there. I haven't thought about making some kind of optimizations that does not require to rewrite reactors as nuclear boilers and cut the entire heat/steam/water part to save performance (but this will also remove the buffer mechanic).
I wouldn't split it into separate mods because weapons and fuels are the outlet for nuclear waste, so it's basically needed to make the whole uranium thing kinda balanced instead of having chests of waste just pile up and do nothing in the map.
That said, I use U236 since there's no loop to get it back into something else yet, but I can add U234 to be even more realistic and have U236 be reprocessed into U234, I like that, but I'll have to do some research ;)
P.S. yeah i might change portable reactors to be "fissile" instead of "fusion", I just went for it because vanilla's was called like that and I didn't question it in the first place