Both small and medium wrigglers only need 1 noise to be generated. If you return to Lignumis later in the game for the golden modules, you might encounter an issue with insane amounts of enemies being created, dropping your UPS (my four silos alone generated 600k noise). I went from smooth 60 UPS to sub 30 UPS just from the thousands of wrigglers on Lignumis. I'd suggest adding more powerful late game enemies to soak more noise and test your defenses.
Played on version 1.5.1.
Loved the mod though, thanks for the hours of fun!