Using just Lignumis' dependencies everything works fine, as soon as I activate Lignumis itself enemies ignore player 2+, which also includes Demolishers. The recent changelog doesn't mention a fix for it either :(
I'm noticing this issue too. After some tinkering, it seems that non-player 1 characters are made indestructible by Lignumis at some point, because I was unable to damage the player via any means at all, even through other mods.