I've gotten started with Nullius and I'm really enjoying it so far. I'm quite early, just unlocked plastic and I'm working through the ingredients needed for it. The checkpoint system is a great idea, especially for a Angel's-style mod or modpack with many fluids and intermediate steps.

I think a lot of the initial confusion, the "How do I research the first technology?" question in the FAQ, is because you've got an unusual way to start, and players that aren't expecting it are a bit confused. I read the FAQ before I started, and I was still stumped and needed to go back and re-read that section. For me, the following could've helped. These are ideas, and as with all player ideas, feel free to take them with a grain of salt :)
- The piece of the crashed ship called "Landing site lab" should be called "Broken landing site lab" or something, to indicate that it is not functional.
- The first technology should include some basic instructions, rather than "Analysis of local mineral composition and soil conditions.", I recommend something like "Clean up the broken landing ship, then build a Laboratory 1 and instruct it to scan local mineral consumption and soil conditions."

I wondered too and if you came from a vanilla run where a lot of players want to keep the crash site as decoration you have a hard time understanding you have to deconstruct it.
I also fiddled with the broken lab and generator and wondered how i get power poles until i saw the deconstruction results.

Pro tipp: Research, build what you have researched, repeat.

the checkpoints are great to have a guiding light through the research tab.