I've noticed that ducts relatively quickly lose pressure even over "short" distances. I know this is mostly due to Factorio's fluid system and the fact that I'm basically producing just about exactly as much fluid as is consumed.
Still to get the pressure I need at the end points I have to set up "pumping stations" every now and then. Just an outlet connected to an inlet to keep the pressure up.
(See https://i.imgur.com/omQYBkz.png for example.)
It wold be nice if you could include something like that as a single entity, maybe using a bit less power than the 360kw I'm spending now to basically work around an engine limitation.