Build your base on a platform that warps from planet to planet and escape biters before they overwhelm you.
Large total conversion mods.
Augmented or new ways of transporting materials - belts, inserters, pipes!
New ways to deal with enemies, be it attack or defense.
Changes to enemies or entirely new enemies to deal with.
Map generation and terrain modification.
Changes to power production and distribution.
When I get biters spawned as incoming waves they can fly over water, which seems a bit broken.
https://imgur.com/a/8ICoXFk
Thats intended. Without it I would not be able to send attacks on player in some rare cases