Build your base on a platform that warps from planet to planet and escape biters before they overwhelm you.
Large total conversion mods.
Augmented or new ways of transporting materials - belts, inserters, pipes!
New ways to deal with enemies, be it attack or defense.
Changes to enemies or entirely new enemies to deal with.
Map generation and terrain modification.
Changes to power production and distribution.
Am I missing a reason to research any of the space techs (thruster/asteroid processing/etc)? Can/should they just be disabled by the mod? I think they can create confusion about future warps.
There will be a way how to connect your warp platform and space platform (after the win condition research) It just just not fully tested yet