First off I found this mod a fun little challenge.
As with the title, if you start on Vulcanus with the "Any Planet Start" mod you will be needing to do researcher in space out from getting off that lovely hellscape. This is do to the "Vulcanus cargo drops" not allowing you to drop off Space science to unlock the "Vulcanus cargo drops" nor the "Space Platform Thrusters" to get to any other planet. Maybe a change that to unlock "Vulcanus cargo drops" you just need to have a Cargo Landing Pad on the planet, having it more of a "yes/no" trigger to drop things off on Vulcanus, or it just not needing space science just the normal ones +Vulcanus science to unlock it.
Another suggestion to is to reduce the starting Calcite patch; after getting every thing with upto Military and Chemical science, using up about half the starting area, and killing the first (of many) Small Demolishers to expand, the patch was maybe only 1/3 used.
I also found that the Medium Demolishers were a little underwhelming; Small ones cast me ~1000 Red rounds and ~100 turrets (loosing a hand full of them doing so) to set up and kill one. Medium Demolishers needed only about 3 times that (loosing quite a few turrets per kill) was expecting that to take a medium one down a combination of turrets/poison/destroyer bots but nope just more guns, im sure a small and on the numbers for them is all that's needed but its just my 2 cents on them, never needed to kill to Large Demolishers so can't say anything about them short of rail weapon like normal to kill one.