When you need to call down the thunder to deal with those pesky biters, launch a rocket with an ion cannon into orbit and show the bugs who's boss.
Update for Factorio 2.1
Bro, can I somehow disable the "Ion cannon ready" sound warning? It's okay if it's one or two, but now I have 10 guarding Nauvis while I stroll around other planets, and it has become rather annoying. It would be sadge to turn auto-targeting off; perhaps I missed something where I can disable the sound?