When you need to call down the thunder to deal with those pesky biters, launch a rocket with an ion cannon into orbit and show the bugs who's boss.
Update for Factorio 2.1
but what's the differences in effects of the MK2 impact compared to a MK1 orbital ion cannon ? is it more powerfull ? can kill worms on vulcanus? larger area ?
does ion cannon damage increase with laser turret technoly upgrade ? or maybe a dedicated tech ?
Mk2 has an increased area and 10 times more power to kill Nauvis Behemoth worms with one hit.
not yet implemented to kill Vulcanus Demolisher "worms", but can kill big pentapods on Gleba.