Having a bit of trouble here with the targeting system. Shortcuts For 1.1 picks up the Ion Cannon Targeting Remote as it should and hides the recipe to craft one...but for some reason it's not actually functional. The Ion Cannon UI says I've got one launched and ready to fire, but the targeting shortcut button stays blocked (like the exoskeleton/roboport toggles if you don't have them in your equipment grid). Anyone else have this issue or know how to fix it, other than uninstalling Shortcuts For 1.1?

"Shortcuts For 1.1 picks up the Ion Cannon Targeting Remote as it should"
no it should not! (but you can disable it in settings) Ion Cannon has its own shortcut.
If you use the shortcut, you don't need to build the remote as item.