It would be really nice to have an "Expendable" Option in the startup options with the number of shots fired (0 being unlimited). Setting these to a 1 hour charge is the current work around I'm using but I'd rather have the option of 10-20 shots per launch with a 5 min fire rate, that make this a powerful but expensive weapon rather than a ramping win button.
It's roughly 40K of mined resources and 75K oil (not much) without modules. Each nuke requires less than 3K mined (2.2K uranium and 900 other), 8k oil. At 15 shots that makes it roughly equivalent (and honestly a better deal since Uranium is rarer and is not affected by Prod Modules).