Adds very large pipes with enormous throughput capabilities.
Mods introducing new content into the game.
Augmented or new ways of transporting materials - belts, inserters, pipes!
Things related to oil and other fluids.
Right now iif I have 2 side by side (i.e. one going underground, then immediately back up) one can not walk between those 2 halves. This is possible with normal underground pipes ;) Nice way to get a way to pass with as little space use as possible.