While attempting to add to a small save with one train and no stations:
Error while running event cybersyn::on_configuration_changed
__cybersyn__/scripts/migrations.lua:331:attempt to index field 'manager' (a nil value)
stack traceback:
__cybersyn__/scripts/migrations.lua:331: in function 'on_config_changed'
__cybersyn__/scripts/main.lua:952: in function <__cybersyn__/scripts/main.lua:951>
Edit: If I enable the GUI setting, the error no longer occurs.