something could be fun to have an optional startup setting that wipes part of your research whenever you go through a wormhole, like wiping your infinite techs or just the wormhole unlock tech, as a way to "test" how fast you can setup and research to your previous level of tech.

I like it! There was another thread about someone wanting the "roguelite" approach where each reset gave you more productivity/damage bonuses as a baseline, whilst wiping all other technologies.

What do you think?

A player would keep their space platforms but they wouldn't work anymore: no recipes for most things until research completed

quickly chiming in here, with the suggestion to lose infinity researches, but keep the bonuses (basically a cost reset for infinity researches).
In matters of what other research one might want to lose, you could make it dependent on science packs. Maybe someone wants to lose everything post space tech, so while they would have to go down to the planet to research some of the recipes on their space ship, they could just simply build a rocket silo again. Maybe someone wants to lose everything that needs military science, or specifically gleba science.

However, I'd wager that wiping (parts of) your research kinda only holds meaning if there's a reason why you couldn't simply just jump the wormhole again (especially if you managed to implement my idea of cost resetting infinity researches)