Oh, ok, so you're before oil and already at big biters, that makes it tricky... Hmm, The only suggestion I have, is to rush flamethrower turrets, if they are still red/green/military research. For defense until then, densely packed scatterguns followed by 2 - 4 layers of heavy MG turrets. If you're fighting manually as well, grenades are great at clearing small stuff.
Reason vanilla gun turrets have both +bullet and +turret damage upgrades, is they actually need them lategame to be of any use - behemoth spitters have a range of 16 VS 18 on gun turrets, they will always exchange fire - so turrets have to out-DPS behemoth spitters by quite a lot to chew through 1500 health each spitter has (with only a mealsy 400 HP and no resistances on the turret, so it dies easily to spitters).
Same reasoning goes to Scattergun Turrets - they are bulky, but lack protection of walls from melee enemies and DPS without the turret damage upgrade against behemoth biters is too low to make a sizable dent in them (with maxed non-repeatable research, when turret damage bonus is taken away, gives estimated 1.5k DPS with uranium ammo, assuming all pellets hit, VS 4500 HP and 12/10% resistance on each behemoth biter) - turret will get like 2 shots off before it gets swarmed and takes a pounding.
Other modded turrets don't have this problem - they are bulky (1500 HP and resistances), and long ranges means they clear biters without being at risk of taking serious damage themselves. That's why everything else only gets one damage bonus (either +ammo damage for ballistics, or +turret damage for energy) - they have much bigger time window to apply the damage they have and not die themselves.
As for turret composition, outside of Light Cannon -> Dual Cannon, there are no direct upgrades, each turret is a tradeoff between various values. Replacing all HMGs with gatlings is a bad idea - if you do this, you lose the overlap, as gatlings have narrow firing cone. I'd instead recommend either swapping HMGs for gatlings in hotspots (replace 2-3 in places where gatlings will shoot forward anyway, and leave HMGs to the left/right for overlapping firing cones), or replace entire first row, and move all HMG's behind gatlings to create a second row. In general, my modded turrets have the best result when you mix them to cover each other's - they are complementary, not competitive with each over.