magu5026, some other mod is editing technology costs or you've set the config to something ridiculous. check your startup-config settings for anything looking like it edits technology/science costs (or try backing up your modsettings.dat file somewhere else, deleting it, and rebooting the game to see if that fixes it---means you set something in the config to something stupid).
If the science is still way too high, disable any content-adding mods that edit technology/science, keeping omnimatter with whatever utility mods you have. then, keeping notes in a program like notepad++, relaunch the game after adding mods in groups of 5-10 until you encounter the issue again. this is a fairly straightforward method of troubleshooting if you don't know straight away which mods may be the root cause