The mod Observed trains out of fuel slowly keep rolling on (2.0.0) caused a non-recoverable error.
Please report this error to the mod author.

Error while running event observed-trains-out-of-fuel-slowly-keep-roling-on::on_nth_tick(600)
Trying to change direction of automatic train moving on a path.
stack traceback:
[C]: in function 'newindex'
...d-trains-out-of-fuel-slowly-keep-roling-on/control.lua:16: in function <...d-trains-out-of-fuel-slowly-keep-roling-on__/control.lua:1>

Using Minitrains with early PYmini train mod

got a save?

https://www.dropbox.com/scl/fi/2xrno88xa5ebyj606irl4/Test-184.zip?rlkey=nlo3eadxqag7defup3socjuk0&st=3kfnodqb&dl=0

Lost OG save had to make a test one. Remove all fuel from a train then go into map view.

Failed to load mods: The given sprite rectangle (left_top=0x0, right_bottom=128x128) is outside the actual sprite size (left_top=0x0, right_bottom=64x64).
If this is being used as an icon you may need to define the icon_size property.
See the log file for more information.: pyalienlifegraphics/graphics/icons/auog.png

looks like your collection of mods is referencing sprites by their incorrect sizes, the only way it loads for you is because of the order you've installed mods in.

please share your crop-cache.dat as well.