Yeah, I had the optional dependencies as I was planning to add in compatibility, but ultimately I ended up with so much customization and jank in the mod that I couldn't really do that without having things take twice as long. I will say that they may work together, but play at your own risk. There are other sources for jank mods other than the dependencies if you want to look those up, like a recent reddit post on the factorio reddit.
Also, a lot of the mods I'm planning to mix into this one in a "light" way. There will be entities placeable off grid, but not all of them will be placeable off grid. So, the game isn't just too overpowered by awful mods, but you still get to experience and need to adapt to each sort of awfulness.