This is a performance problem report. I tried to capture the performance issue, but the nature of it makes it difficult to do so.

What did you do? - Played the game on a map with a huge amount of trees.
What happened? - The game stuttered/flinched/froze-for-an-instant corresponding in a frequency to the tick update setting of the Treeees mod. It is practically clockwork.
What did you expect? - I expected this mod to not stutter gameplay.

Disabling the Treeees mod makes the stutter go away.

Factorio Version: 1.1.25
Treeees Version: 4.4.2

No Issues Screenshot: https://drive.google.com/file/d/1yVl9as5XhBF_3NUs6-008z-z7lqwg_wm/view?usp=sharing
Yes Issues Screenshot: https://drive.google.com/file/d/1fYxGCZ1jt8Qbe1EAYERrY2OrqsUnuBVZ/view?usp=sharing

Save File: https://drive.google.com/file/d/1eTX2x3DCpYRcOGGyzQrnRWoejxr0o_sA/view?usp=sharing
Log (verbose): https://drive.google.com/file/d/1EluoI8OzfXpx9G3OY-T1wY-eN6pm3YqH/view?usp=sharing
Performance Spreadsheet: https://drive.google.com/file/d/1qrxf0XOVnJ-BkiYijFhMNYXXtNuEY6Zy/view?usp=sharing

Thank you very much for the bug report.

The stutter should be replaced with longer loading times in version 4.4.3