Build your factory as a Spidertron from the start! Instead of unlocking better weapons and armor, unlock upgrades to yourself.
Mods introducing new content into the game.
Transportation of the player, be it vehicles or teleporters.
New ways to deal with enemies, be it attack or defense.
Any chance of fixing it to work with the nanobot mod?
Not really, see https://mods.factorio.com/mod/SpidertronEngineer/discussion/5f53989c3affea2aa74c0d45 If you turn on 'Compatibility mode" then it will let you craft the nanobot emitter and you'll be able to exit the spidertron to use it.
I see. Thanks!