With this mod is enabled when enemies die they drop small Alien Artifacts, If you have other mods that causes Bitters(And other thiongos) to attack each other, they will still drop these Small Alien Artifacts, thing is these Small artifacts can accumulate over time and cause serious lag issues.
If you have already have this problem here is a snip of code that will remove all entities on the ground, just hit the tidal key and paste the code in.
/c
for chunk in game.surfaces.nauvis.get_chunks() do
local top, left = chunk.x * 32, chunk.y * 32
local bottom, right = top + 32, left + 32
for _, ent in pairs(game.surfaces.nauvis.find_entities_filtered{area = {{top, left}, {bottom, right}}, name ="item-on-ground"}) do
if ent.stack then
ent.stack.clear()
end
end
end