Inspiration from DoshDoshington's seablock retrospective - https://www.youtube.com/watch?v=BzxMUabck3E
My suggestion is removing the bio-crystal based circuit boards from tier 0 modules, and shifting the circuit/logic boards up a tier, end result being that the bio-crystal tiers line up with tier 1-3 modules instead
This would make it possible to get to space science without doing any serious bio processing, but still keeps the big boosts (and beacons) behind a load of complexity. Maybe even nerf affected modules a bit if it feels neccessary