Strangeness appears to be happening. Here is the information as I learned it.
When I posted this initial bug report, I was getting the error message when only Arcanyx+Dependencies was turned on. This meant I couldn't actually get to my settings to look at what I had changed.
Later, with Arcanyx turned off but Iridescent Industry turned on, I turned on Safe Integration.
After reading your response, I decided to try gain. The error message is gone now. I guess Safe Integration has fixed my problem? So I can actually get to my settings to tell you what I changed. Due dilligence suggests I should do that.
Arcanyx
Prismite on Nauvis: On
Mythril Required for Nuclear: Off
Iridescent Industry
Safe Integration: On (Was off when I got the error message)
I don't understand why changing only Prismite on Nauvis and Mythril Required for Nuclear would break my ability to load the mod.