i quite enjoy having a lot of the options you've added, the thorium/tritium and the "no waste power" on reactors is great. but the rebalanced amount of stuff from uranium centrifuging feels.... off? like 10x the output of 238, 235 and probably ~15x the output of mixed pellets from gas feels a little absurdly powerful? for me this wasnt really an issue until recent, because another mod i had (heated fabrication) allowed me to ignore that change, but as of recent its changed so i cant anymore

"a little absurdly powerful" - what i mean by this is that im 95% sure you can have a completely closed loop with no uranium ore coming in and generate more uranium than you use, even if only ever make fuel items. vanilla transplutonic was only nearing there when you had high productivity and were irradiating all the ampules for stuff again but i think the 10x uranium per 50 gas and the 100x no.6 for a set of pellets puts you siginificantly past that

I will look into it for the more production than use (close loop no need ore)
The 50 gas = 10 uranium is normal with the logic i use as 1 gas =1kg and 1 item = 5kg. but with all the step i might have miss a ratio.
You should be able to reduce the energie of each fuel in the setting to offset it for the moment

I didn't see a problem what setting did you use.
I did 100 spent uranium fuel rod (500 Gj) and i got after recycle 53 uranium fuel rod (265Gj) + 3 neptunium fuel cell (3Gj) + 7 MOX fuel rod (52.5Gj) for 320.5Gj and some left-over items

the energy lost is in fact not much (in ideal world as only the U235 that split releze energy and some of this energy is used by the U238 to become Pu and then be able to split.

As example in 100 U you have 5 U235 and 2.5U235 will split and give energy in the end you have left with 75U (72.5U238 and 2.5U235)+20Pu(from U238 that got transform) and 5% of fission product.

But you should completely deactivate the recipe tweak if you want now, I fix a bug in the mod setting that ignore the level of recipe