So I've noticed that there are "chunks" missing out of the resource patches that are remarkably similar to nearby bodies of water. It's almost as if the generation was shifted slightly from the location where it was "supposed" to be.

I've noticed it's not always shifted to the west as shown in my screenshot. it seems to be shifted towards the direction of the starting area. So, resource patches to the south are shifted north. Resource patches to the west are shifted east, and so on. Also, it seems to get more pronounced as you get further away from the starting area.

https://imgur.com/1NgByJM

I can provide more screenshots if you like. Screenshot was made using 5.0.17 on Factorio 0.17.66 b16866

It's an interesting case. I don't recall seeing those... but it might be caused by small trick RSO is using when spawning patches. Can you provide a map string or save file so that I can take a look?
It seems like for some reason collision avoidance algorithm is not resetting properly which leads to what you are seeing. And offset you see would be equal to 1 chunk in any direction.

Exchange String:

eNpjYBBkcGIAgwYHILbjYEnOT8xZvWqVHQODA0jEnis5v6AgtUg3
vygVWZgzuag0JVU3PxNVcWpeam6lblJicSqICzXZniOzKD8P3QTW4pL
8PFSRkqLU1GKIRgjmLi1KzMsszUXXy8B4z8RvR0OLHAMI/69nUPj/H4
SBrAdAGx8wMMCsZmAEisEAa3JOZloaA4OCIxCD/c3IwFgtss79YdUUe
0aIGj0HKOMDVORAEkzEE8bwc8AppQJjmCCZYwwGn5EYEEtLgFZAVXE4
IBgQyRaQJCNj79utC74fO2DH+Gflx0u+SQn2jIauIu8+GK2zA0qzg7z
ABCdmzQSBnTCvMMDMfGAPlbppz3j2DAi8sWdkBekQAREOFkDigDczA6
MAH5C1oAdIKMgwwJxmBzNGxIExDQy+wXzyGMa4bI/uD2BA2IAMlwMRJ
0AE2EK4yxihzEgHiIQkQhao1YgB2foUhOdOwmw8jGQ1mhsw4wDZC2gi
KkgBzwWyJwVOvGCGOwIYghfYYTyH+Q7MDAgAjODdm5/UAADrCKRu<<<

I generated a fresh save file with minimal mods from this string and used creative mod to generate most of the map:
https://1drv.ms/u/s!AvY-J1oitdel5CHmvnWnTQ1t8v_h

Thanks for the save and map string.
It was a tricky one but should be fixed in 5.0.19.