This mod is great. Lots of stuff to do. However, the mineral reserves being permanent makes designing a self-expanding factory, which is a much more interesting goal, next to impossible. Additionally, they allow you to get infinite resources without forcing you to resort to really stupid bioprocessing. Could you please make them finite, or at least add a mod setting to do that?

If the author doesn't want to do this, then you can easily make these changes yourself. Just unzip this mod into a folder in the factorio mod directory and delete the zip. Then edit pyhardmode\prototypes\mining.lua. Go to line 29 and you'll see a for loop that looks like

for _, resource in pairs(resource_rocks) do
...
end

just delete all of that. aka line 29-44. Save and that should what you want. You'll have to reapply this fix every time you update this mod fyi.

Just add an ore eraser mod
Trust me, you will be so overfilling with organ parts that you'll want to atomize just to get rid of stuff. Don't underestimate the amount of dead animals needed to be killed in pys :)