Would there be a way to make an option to remove loaders on sides from any big factories (do keep pipes)?
The reason is that if You use Bob's inserters and level them up enough, they can be... ALOT faster than any belt can possibly throughput, and if there are loaders, they try to release the payload onto them instead of the factory.
Thanks!

A setting to not generate loaders at all? Sure, that should be possible.
In the mean time, you can remove loaders by hand (just pick them up) or you can rotate them so they don't produce output (which is the default rotation).