The crash on startup is an easy enough fix. Only Gleba removes the map gen data from the other planets completely rather than just hiding it/not using it (which is likely to break compat with other mods besides just Simple Seablock), it's simple enough to add some checks to prevent a crash.
However, once that is fixed the game essentially becomes a regular Simple Seablock game with an early recipe to unlock the Biochamber, which you can't actually craft because there is no way to get nutrients. So to properly support the 2 mods together I'll need to spend some time figuring out how to properly merge the tech trees. 2 obvious ones are removing the recipes for copper and iron ore from sediment and unlocking gleba foraging from the start.
Another trickier item is that you're actually on Nauvis when playing the mod, it's all smoke and mirrors to make it look and act like Gleba. At a minimum I'd probably need to take the Gleba seablock layout and apply it to Nauvis, and see what other consequences show up as a result.