I experience quite a lot of stuttering, every second or so, when I tried this mod. So I took a look at the code and made the following changes, which seem to fix it. Feel free to use these changes.

As far as I can tell, the issue stems from the fact that the current code removes the resources from the entire chunk, instead of only removing resources from the chunk that was generated, so I added the surface and area parameters to the remove_ores_on_Nauvis function and removed the loop over all surfaces inside this function.

-- control.lua
local function remove_ores_on_Nauvis(surface, resources, area)
    if surface.name ~= "nauvis" then
        return
    end

    for _, resource_name in pairs(resources) do
        for _, entity in pairs(surface.find_entities_filtered {
            type = "resource",
            name = resource_name,
            area = area
        }) do
            entity.destroy()
        end
    end
end

script.on_init(function()
    for _, surface in pairs(game.surfaces) do
        remove_ores_on_Nauvis(surface, resources_to_remove, nil)
    end
end)

script.on_event(defines.events.on_chunk_generated, function(event)
    remove_ores_on_Nauvis(event.surface, resources_to_remove, event.area)
end)

Would it not be easier to create a map setting that dissables the ores from spawning on Nauvis then to remove the ores by a script?

I can confirm the script changes above improve the performance significantly. This particularly helps when using the Blueprint's Sandbox mod. Prior to this script switching to the blueprint sandbox caused the game to slow to an absolute crawl.

Thank you very much and sorry for taking so long!

I added the updates to the mod script and additionally edited the SpaceEx default Map Preset.

Its live with 0.3.0