Misanthrope is way, way too difficult for me. The mod made it sound like it would just make the biters less stupid, improve their attacking and whatnot.

But I just got attacked by half a dozen big biters with an army behind them when I was only just getting solar power completely established at my base. 20 fully upgraded turrets with 30 ammo a piece didn't scratch that army, and the 25 grenades with damage upgrades took out the small fries but the big biters were just too much and overwhelmed me.

I knew this would make the game harder, but this is just impossible for a casual player!

Could this have had something to do with starting off with 'Enemy Bases' being 'Very big' when generating the map?

Would setting it lower slow when big biters start coming after me?

Biter Base size certainly affects the size of the attacks.

Evolution is also sped up, since most buildings generate 10x pollution. I wouldn't know that Big Biters would already spawn that early, though. At least didn't happen to me yet, with Bob's mods.