The knowledge of Plasma Clips will come handy if you can't find oil spots deep into the mid-game, just patch up the good old Piercing Rounds Magazines with some Alien Technology.
Use these in your regular weapons like Sub-Machine Gun or shoot it from your vehicles for greater range!

Pros:
- Can get that very needed little extra DPS
- Vanilla friendly

Cons:
- Costs Alien Artifacts

As much as it can come handy in certain situations, you should still use it wisely as it eats up all your Alien Tech if you start using it as an all purpose ammunition...

Hooooops! One last thing before I forget! :)
It does plasma damage! That means zero resistance bonus, so it can eat up alien bases and worms like candy!