Thanks MagmaMcFry!
So, I assume when a factory is destroyed, the factory interior space still exists, but is no longer accessible; is there a way to rebuild a factory that was destroyed? (Reconnect the interior space with the factory item).
I think I saw there is a command "/give-lost-factory-buildings" that will cause destroyed factories to appear in your inventory, but is there a way without the command console? (Like building a new factory and some how assigning it to an existing space that is not attached to another factory).
Anyways, thanks for your detailed answer above, that's what I was wanting to know before really diving it, this mod looks awesome!