Clicked outside of the locomotive!
Also playing with: Multiple Train Control, Train and Fuel Overhaul

Can't reproduce it with the given information. Please provide a save or a more detailed way to reproduce it.

https://www.dropbox.com/h?preview=Space_Exploration_Laptop.zip

i dont know what to use for file share, so i hope this works

This link doesn't work. There should be something like "Share this file" or try https://wetransfer.com

Seems I can't recreate the crash on my save either way. Sorry for the bother!

link to my save:
https://we.tl/t-3bVUfb7vOL

No problem.
I think it's unlikely because of FARL, ctrl+clicking on an entity is fast transfer of items, and FARL does nothing if that event is raised.
The next time you get a crash:
- maybe take a screenshot before confirming the message (in case it's a script error, when it's a hard crash it is most likely a Factorio bug since mods shouldn't be able to hard crash the game)
- copy the factorio-current.log