No signals can be set in your combinator
Your combinator does not send any signals.

Connect it to a circuit network. You can use a constant combinator or a pushbutton connected to the Artillery Combinator with a wire to input the signals. It fires every tick that it gets a Artillery Remote signal (the item you would otherwise use to manually target your artillery) so pushbuttons are better for testing. Use X, Y and (optionally) A to decide where to target it. Because no virtual signals means X=0, Y=0 and A=0 which means it will target itself :)

At the bottom of the description, there's links to 2 of my forum posts where I posted example blueprints that show you how it can be used. Those blueprints need "AAI Programmable Structures" mod as well to use.

How reset attack coordinates?

I don't understand the question. Can you explain more what you mean?

i turn off "Constant combinator".....cannon shot
i deconstruct "Constant combinator"........cannon still shot
i turn off "Artilery Combinator"....cannon fu#ing still shot
i deconstruct "Artilery Combinator" cannon fu@%ng still fu!*ng shot
how rest/delete/erase X and Y??

From the description:

Also, this combinator will fire every tick if you tell it to (fires on AR signal and not just the rising edge) so you can fire faster. Use Pushbutton instead of constant combinators if you want to test it manually since it sends a single pulse when you activate it (and it's a must-have mod anyways).

If you used a constant combinator and had it on for a few seconds then you have already ordered your artillery to fire at least a few hundred shots on that spot. If you were careless your artillery will keep firing thousands of shots. There's nothing you can do about it.

That's why I told you to test it with pushbuttons that only send a single pulse when you push them with 'f'.

You messed up after I told you several times to be careful, don't do the same mistake again :)

You can do (in console)

/c for k, v in pairs(game.player.surface.find_entities_filtered{name = 'artillery-flare'}) do v.destroy() end

if you really need them to stop immediately.

New version, 1.0.1 released!
Features:
- New hotkey: "Shame and regret". When you need it, you'll know what it does. I pity those who do need it.

Default hotkey is "Pause" / "Pause Break"