can it be setup to "left click" toggle switch and "e" open setup window?
I'm not sure, I'll have to investigate. Since the original authors never suggested it I would assume is not possible.
also is there a possibility to create another switch wich hast 2 on states with different signal outputs?
I'm not sure how the user interface for configuring the signals for each state could work, the button is a constant combinator under the hood. What you want is also achievable by adding 2 constant and 2 decider combinators, each decider would output the contents of one constant combinator depending of the state of the switch button.