(sorry for my eng dude, I'm from Ukraine)
So, I make the full automation for every quality using circuit network and tested the most prices for upgrading Items and I can give feedback
My options:
"allow-multi-step" disabled > so I need to upgrade resources to higher quality
final cost are set to 2.5
most of items are very cheap for 1 > 2 upgrade, cuz my factories can make 12k/sec of upgrading resources, but I can't use more than 1500/sec with most items (only artillery shells and 3rd modules cost good)
upgrading for 2 > 3 are normal for price, because currently with my factory expanding I can make only 1600/sec 2nd quality upgrade resource
upgrading for 3 > 4 a lil expensive cuz a large factory can't create a big amount of 3rd quality resource, cost is normal only for regular resources
upgrading for 4 > 5 is useless when cost bigger than 150, it's worth only for upgrading something in a little amount such as turrets or buildings
So my suggestions:
1 > Make separated adjustment for every quality cost
2 > Make "tiers" for resources, like: ammo(tier 1) have own cost, science pack(tier 2) and buildings(tier 3) has another cost, tier 0 is regular adjustement
3 > Remove the cap of minimum 5 resources for upgrade, u can down cap 1res, and make that recipes every time upgrades only 1 item, I hate upgrading 2 electric drills xD (default options)
more about why I hate when recippe has bigger than 1 upgrading item - my automated upgrade factory contains 8 buildings, and sometime building receive only 1 upgrading item when recipe requires minimum 2 xD
4 > Separated cost adjustment specially for upgrade items