So after one complete run and 3 abortet runs a little feedback, keep in mind thats only how i feel about the mod its not bad at all.
I played many runs with Vill's Recipe Randomizer before factorio 2.0 and it was far far worse every time than this mod.
The biggest problem for me after playing for a while , it felt like that the items in the game just had there icons shuffled at one point.
I know there is an option for that (i never activated that option) but even without that option it felt like that. Sure the items a recipe needs is more than normal but there is some kind of balance behind it that its not getting too off kiltFr.
For some reason there where not really any ridiculous long and super expensiv production chains, granted when you got to the other planets and wanted to produve the sciences you had to get creativ lets say. 
Another problem , when i got to a new planet for the first time there was a bunch of techs in the way before i could play on the planet...let me give you an esample from my completed run. I needed Fulgora because Vulcanus and Gleba where behind Fulgora tech and i wanted that recycler to make my life easier on the other planets.
Fulgora => that ruin you need 
Gleba => collect that iron/copper stromatolite whatever its called
Vulcanus => mining quality 2 module ( what i got as Calcite on Vulcanus)
Gleba => the other stromatolite thing
Fulgora => i cant remember what i needed to craft but after that i could craft the recycler
that was pretty anoying, in the end i used that teleport back to nauvis hotkey for every planet, because i did not wanted to wait hours on the planet to build q rocket silo and than flew off to the next planet, so i skipped that. I dont know how you could make that better with the amount of randomization in the mod.
I can not remember if it was randmoized or not but the special building from each planet, please randomize the planet on which they have to be crafted :)
Its not that i dont like the randomization with the planets ... just that i had to travel to each planet first to unlock the techs so i could start playing on the planet.
those where my major problems the rest is just because i got unlucky because of randomization... those nuclear bombs i got from asterroids where funny but blew up the ship when used :/
Aquilo wasnt even that different from a normal playthrough as you need to deliver everything there todo anything anyway...it was more you needed to deliver sure but at that point i had my fleet from the other planets to deliver all the stuff i needed.
reaching the edge of the solarsystem was a different challenge because of randomization i got pretty unlucky and could not produce any ammunition on the platform (well i theorethically could but the place i would have needed was just far more than some storage space with a few thousand of ammunition inside them)
Another thing the randomized starter resources are nice for the first or second time but thats it because with either a stone furnace or bricks as a starter ressource you almost can jumpstart a furnace stack, here i noticed the missing complexity the most from Vill's Recipe Randomizer where i needed in one run 3hours to craft the first power pole so i could start researching... its not that i want a randomized marathon run but i got just that unlucky with the mod.
Overall its o good mod but im probably the only one that wishes it would be more punishing/crazy in the randomization aspect.
if possible i would have liked a little more contol over how much "worst" the Bias and chaos could get, like an extra option where i could set how much more items a recipe needs or something.
As writing this i noticed there where a few fixes in later mod versions so take it with a grain of salt.
my complete run was somewhere version 0.3 to 0.3.2
the 3 abortet runs where 0.3.6 or 0.3.7
oh yea uhm i would also be nice if the recipes have more fluids in them in my runs there where not many of them... also would be nice to hafve fluids in recipes where before were none.
Just so as we had talked in another thread the amount of ingredients in a recipe randomized would also be a nice addition, if its not allready in there.
I will definetly make a new run with the 0.3.13 version now and see how much has changed... and obviously i will let the world burn:) but not today or the next week... at the latest over christmas/new year i will start at least.
Regards Vivio
The Janky Factory must grow :P