No ore patches, expand from a small island. Also install the 'Sea Block Pack - Official' mod for a complete modpack
Large total conversion mods.
The only thing that's missing, and it should be simple to fix, is compatibility with pyanodons
Seablock requires Angels. Pyadons is incompatible with Angels. Doesn't sound like a simple fix.
There is an intermediary here which makes them compatible - https://mods.factorio.com/mod/PyCoalTBaA. Maybe it makes a good place to start...
py mods change a hell of a lot. the compatibility is one thing, the way that py mods would change the game is totally different. you can grow stuff from nothing and turn it into coal, that one thing alone is gonna massively change balance.