If you don't play with a quick start / early bots mod, I would recommend researching Lumberjack and Arborium quickly. Otherwise you'll probably go crazy from chopping trees all day.
Other than that I would say just approach it like you would any other big modpack and let me know how it goes. I've just started my own map with this new version as well (of course I did testing, but not a full playthrough yet).
There might be one thing I need to fix today. MadClown's Science and the Science Bottles mods weren't working together. I reported it to Jackzie (author of Science Bottles), but since I didn't know how responsive he would be I went ahead and fixed it in Stitching. Turns out Science Bottles got updated within hours, so I most likely need to remove my fix.
Edit: One last important thing - brevven's Aluminum mod is very new and could see breaking changes as he updates it. I included it both because I like it in it's current state and to get to a final mod list. But since it is technically alpha, you may want to keep an eye on changelogs, don't update it, or leave it out.