When you need to call down the thunder to deal with those pesky biters, launch a rocket with an ion cannon into orbit and show the bugs who's boss.
Mods introducing new content into the game.
New ways to deal with enemies, be it attack or defense.
I think that it would be a cool idea if you could make satellites that will target for you, or just add a research that will give normal sattelites that capability
That's a good idea, I might just have a feature like this for the 0.15 update.