Basically if there is an odd number of items that create multiple (IE. copper cable). In my setup I have a yellow chest that just collects random crap that bots will drop there. I feed this into the junk compressor and then have filters that remove the items once they are deconstructed the entire way back to plates, etc. Well, sometimes I end up with an odd number of multi items that then cause the game to crash.
I hope this makes sense. It was a long day for me and my brain isn't functioning to well at the moment =).
