I've recently began playing this mod, and I can't seem to get the factory preview research to work. I've done everything I can, toggled it on in the top left, crawled the the settings, restarted the game and my computer, all that jazz but it only turns on for 1 or 2 frames right as you enter the factory building. I can't figure out what's going wrong.

The factory preview should show up whenever you hover your mouse cursor over a factory building, or hold a factory building item in your cursor, or hover over the substation near the exit of a factory building. Which of these situations does not work?

I doesn't work in any of them, but it does work for the holding it in your hands if you walk in/out of a building while holding it. I don't know if that'll help or not, but it seems important

Can you post a save, or a list of mods you have installed?

Here's my mods (there's quite a few):
AAI industry
AAI signal transmission
Aditional turrets
Alien Biomes
All tiles stack to 1k updated
Base mod
Better Bot Battery
Bigger Artillery
BigStorageTank - Store your Fluids
Bullet Trails
Cargo Ships
Cargo sips rescale (yes it's spelled sips, I know it's wrong but the mod's name is fucked)
Corpse Marker
Cursed Filter Mining Drill
Dirt Path
Electric Furnaces 2x2
Epic Artillery Sounds
Extended Vanilla: Mining Drills
Factorissimo2
Fill4Me
Floating Damage Indicators
Fluid Trains
GDIW - Gah! DarnItWater!
GhostPlacerExpress
How Far Has it Been?
Infinite Buffer Chest
Infinite Buffer Fluid Tank
Infinite Laboratory Speed
Infinite Repair Pack Revived
Infinite Technologies
InfiniteInventory
Infinizoom
InformaTron
Inlaid Lamps Extended
Jetpack
Liquid Ore Conversion
Long and Far Reach
Modular Turrets
MouseoverDeconstruct
Orphan Finder
Petrol-Condensation-Reload
Portals
Rampant
Rampant Resources
Repair Turret
RitnLib
Robot Attrition
Sheild Projecter
Space Exploration
(The many space exploration graphics + postprocess)
Space Factorissimo Updated
Squeak Through
Supersonic High Speed Train mod
Train research for better porformance
Train Skip Fulfilled Station
Trashcan
Uranium Geiger
Voidworks
Waterfill
Where Is MyBody
I can send you my save, but I don't know how to send files over the factorio message boards, sorry ;-;

That's a lot of mods. You could upload your save to some sort of cloud storage and send me a share link.

Hi, i have the same problem too.
My mods from log file:

Aircraft = "1.8.4",
AircraftRealism = "1.4.0",
["Armored-train"] = "0.4.4",
ArmouredBiters = "1.1.4",
Automatic_Train_Painter = "1.1.4",
BeltRouter = "1.5.2",
["Blue-Ghosts"] = "1.1.1",
BlueprintTools = "1.2.1",
Cold_biters = "1.1.1",
Custom_Production_UI = "1.0.0",
Dirt_Path = "1.3.5",
DragonIndustries = "1.105.1",
["Electric-Weapons"] = "1.1.2",
ElectricTrain = "1.1.2",
EvoGUI = "0.4.601",
Explosive_biters = "1.1.35",
Factorissimo2 = "2.5.3",
["Flow Control"] = "3.1.3",
FluidWagonColorMask = "1.1.0",
Hovercrafts = "1.2.1",
InlaidLampsExtended = "1.1.1",
["K2-automated-artillery"] = "1.0.3",
Krastorio2 = "1.2.17",
["Krastorio2-more-locomotives"] = "11.0.0",
Krastorio2Assets = "1.1.0",
Krastorio2RFAC = "2.0.0",
Krastorio2_Menu_Backgrounds_By_TehFocus = "1.0.1",
LTN_Combinator_Fix = "1.1.1",
LTN_Content_Reader = "1.0.2",
LTN_Language_Pack = "1.9.0",
LogisticTrainNetwork = "1.16.7",
LtnManager = "0.4.8",
MiscLib = "0.9.2",
MyRUS2 = "21.9.1121",
PavementDriveAssistContinued = "3.1.0",
["RFM-transport"] = "1.0.5",
RampantArsenal = "1.1.2",
Robocharger = "1.3.1",
Robot256Lib = "1.1.2",
Robot_Battery_Research = "0.2.1",
SSP = "1.1.0",
SchallAlienLoot = "1.1.0",
SchallAlienMutation = "1.1.0",
SchallAlienTech = "1.1.2",
SchallAmmoTurrets = "1.1.0",
SchallArachnidPlatoon = "1.1.0",
SchallArmouredTrain = "1.1.0",
SchallArtillery = "1.1.1",
SchallBeltConfiguration = "1.1.1",
SchallCircuitGroup = "1.1.0",
SchallCombatRobotics = "1.1.0",
SchallEndgameEvolution = "1.1.1",
SchallEntityInspector = "1.1.2",
SchallGeowarfare = "1.1.0",
SchallGunPod = "1.1.0",
SchallInserters = "1.1.0",
SchallLampContrast = "1.1.0",
SchallLandMine = "1.1.2",
SchallLanguagePack = "2021.12.16",
SchallMachineModification = "1.1.0",
SchallMapTag = "1.1.1",
SchallMinorTweaks = "1.1.2",
SchallMissileCommand = "1.1.1",
SchallModulePlacement = "1.1.2",
SchallModules = "1.1.0",
SchallRadarAlignment = "1.1.2",
SchallRadioactiveWaste = "1.1.1",
SchallStartingInventory = "1.1.2",
SchallStartingTech = "1.1.0",
SchallSuit = "1.1.1",
SchallTankPlatoon = "1.1.1",
SchallTankWoodcutting = "1.1.1",
SchallTransportGroup = "1.1.0",
SchallUncraft = "1.1.0",
SchallVirtualSignal = "1.1.2",
ShockTurret = "0.1.6",
StatsGui = "1.3.0",
Waterfill_v17 = "1.1.0",
YARM = "0.8.203",
["aai-containers"] = "0.2.10",
["aai-industry"] = "0.5.11",
["aai-programmable-structures"] = "0.7.3",
["aai-programmable-vehicles"] = "0.7.20",
["aai-signal-transmission"] = "0.4.4",
["aai-signals"] = "0.6.1",
["aai-vehicles-chaingunner"] = "0.6.1",
["aai-vehicles-flame-tank"] = "0.5.1",
["aai-vehicles-flame-tumbler"] = "0.6.1",
["aai-vehicles-hauler"] = "0.6.1",
["aai-vehicles-laser-tank"] = "0.6.4",
["aai-vehicles-miner"] = "0.6.3",
["aai-vehicles-warden"] = "0.5.3",
["aai-zones"] = "0.6.4",
["air-filtering"] = "0.8.3",
["alien-biomes"] = "0.6.5",
["alien-biomes-hr-terrain"] = "0.6.1",
autocolor = "1.1.1",
base = "1.1.53",
beautiful_straight_bridge_railway = "1.1.1",
beltSorter = "0.9.1",
["big-data-string"] = "1.0.0",
["cargo-ships"] = "0.1.13",
["cargo-ships-graphics"] = "0.1.0",
["electromechanical-combinators"] = "19.0.0",
fcpu = "0.4.13",
fixLargeElectricPole = "1.3.0",
flib = "0.9.2",
informatron = "0.2.2",
["inventory-repair"] = "19.0.1",
jetpack = "0.2.13",
["krastorio-2-compat"] = "0.7.0",
lightorio = "1.1.3",
["ltn-cleanup"] = "1.0.17",
["m-microcontroller"] = "0.10.9",
["marine-life"] = "1.1.2",
miniloader = "1.14.8",
robot_attrition = "0.5.12",
scattergun_turret = "7.2.0",
["shield-projector"] = "0.1.3",
["space-exploration"] = "0.5.103",
["space-exploration-graphics"] = "0.5.14",
["space-exploration-graphics-2"] = "0.1.1",
["space-exploration-graphics-3"] = "0.1.1",
["space-exploration-graphics-4"] = "0.1.1",
["space-exploration-graphics-5"] = "0.1.2",
["space-exploration-postprocess"] = "0.5.27",
["space-factorissimo-updated"] = "0.0.12",
stdlib = "1.4.6",
["underground-pipe-pack"] = "1.1.2",
vehicle_physics_again = "1.0.0",
["waterfill-retexture"] = "1.1.5"

I notice that you both have both Factorissimo2 and Space Factorissimo installed. There might be a name conflict involved here if Space Factorissimo still uses the same names for GUI elements as Factorissimo.

I was also experiencing this issue, and can confirm that previews began working again once I removed Space Factorissimo, with one caveat: The preview is zoomed way in; I can only see about half the factory contents, around the center of the factory. This only applies for the file which previously had Space Factorissimo; a new save created after removing SF had no problems.

Edit: There is information on a workaround for this issue at https://mods.factorio.com/mod/space-factorissimo-updated/discussion/6123a517b2af7d993b7d5be5. Note that I still get the zoomed-in issue with the workaround, but figured I might as well link it.