When starting a fresh game the factory input combinator works as intended. After playing through the scenario a little, the combinator stops functioning as intended. I will click it and nothing pops up, and when i click it a second time it opens two menus, the factory item input combinator, and the input item controller, but the input item controller is blank.

I'm not getting an error screen and have no idea what to do to help find the cause of the issue. I only have the scenario, factorissimo mod, and base game active in my mods list.

Link to a screen shot of the menus
https://i.imgur.com/abxsZ3l.jpg

If i start a new game and pick up the tier 3 factorissimo building it also causes the glitch to happen.

You are experiencing the same thing as I was. It is best to install This mod and its dependency (Factorissimo2) in game through the mod menu. There isn't supposed to be a scenario, the mod will just throw you into a tier 3 factory when you start a new freeplay game.

Marking as resolved.